A wound leakage collection device is described wherein a chamber is provided for removing wound leakage material from vacuum tubing, whereby the chamber can easily be removed from a wound and a source of negative pressure. An exemplary device comprises: vacuum tubing having a wall with an external surface, an internal surface, a first end in fluid communication with a negative pressure source, a second end in fluid communication with a wound leakage source, and a portion between the first end and the second end having one or more perforations through the wall; a chamber for enclosing and maintaining a vacuum around the external surface of the perforated portion of the tubing; an absorbent material disposed within the chamber adjacent to the external surface of the tubing; and one or more vapor-permeable plugs disposed in the internal surface between the first end and the perforated portion of the tubing.