PLAYER, MARK R.,CALVO, RAUL,CHEN, JINSHENG,MEEGALLA, SANATH,PARKS, DANIEL,PARSONS, WILLIAM,BALLENTINE, SCOTT,BRANUM, SHAWN
申请号：
CA2791715
公开号：
CA2791715C
申请日:
2011.03.03
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The present invention is directed to substituted aza-bicyclic imidazolederivatives,pharmaceutical compositions containing them and their use in the treatment ofdisorders andconditions modulated by TRP M8, including for example, inflammatory pain,inflammatoryhyperalgesia, inflammatory hypersensitivity condition, neuropathic pain,neuropathic coldallodynia, inflammatory somatic hyperalgesia, inflammatory visceralhyperalgesia,cardiovascular disease aggravated by cold and pulmonary disease aggravated bycold.(see formula I)
