CALVO, Raul,CHEN, Jinsheng,MEEGALLA, Sanath,PARKS, Daniel,PARSONS, William,BALLENTINE, Scott,BRANUM, Shawn,PLAYER, Mark, R.
申请号:
DK11709244
公开号:
DK2542552T3
申请日:
2011.03.03
申请国别(地区):
DK
年份:
2017
代理人:
摘要:
The present invention is directed to substituted aza-bicyclic imidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by TRP M8, including for example, inflammatory pain, inflammatory hyperalgesia, inflammatory hypersensitivity condition, neuropathic pain, neuropathic cold allodynia, inflammatory somatic hyperalgesia, inflammatory visceral hyperalgesia, cardiovascular disease aggravated by cold and pulmonary disease aggravated by cold.