Raul CALVO;Jinsheng CHEN;William PARSONS;Mark R. PLAYER;Carl ILLIG;Daniel PARKS;Sanath MEEGALLA
发明人:
Mark R. PLAYER,Raul CALVO,Jinsheng CHEN,Carl ILLIG,Sanath MEEGALLA,Daniel PARKS,William PARSONS
申请号:
US13364352
公开号:
US20120202856A1
申请日:
2012.02.02
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention is directed to benzimidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by TRP M8, including for example, inflammatory pain, inflammatory hyperalgesia, inflammatory hypersensitivity condition, neuropathic pain, neuropathic cold allodynia, inflammatory somatic hyperalgesia, inflammatory visceral hyperalgesia, cardiovascular disease aggravated by cold and pulmonary disease aggravated by cold.