Player, Mark R.,Calvo, Raul,Chen, Jinsheng,Meegalla, Sanath,Parks, Daniel,Parsons, William,Ballentine, Scott,Branum, Shawn
申请号:
AU2011223566
公开号:
AU2011223566B2
申请日:
2011.03.03
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
The present invention is directed to substituted aza-bicyclic imidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by TRP M8, including for example, inflammatory pain, inflammatory hyperalgesia, inflammatory hypersensitivity condition, neuropathic pain, neuropathic cold allodynia, inflammatory somatic hyperalgesia, inflammatory visceral hyperalgesia, cardiovascular disease aggravated by cold and pulmonary disease aggravated by cold.