Raul Calvo;Jinsheng Chen;Shawn Branum;William Parsons;Mark R. Player;Daniel Parks;Sanath Meegalla;Scott Ballentine
发明人:
Mark R. Player,Raul Calvo,Jinsheng Chen,Sanath Meegalla,Daniel Parks,William Parsons,Scott Ballentine,Shawn Branum
申请号：
US13034922
公开号：
US08680098B2
申请日:
2011.02.25
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention is directed to substituted aza-bicyclic imidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by TRP M8, including for example, inflammatory pain, inflammatory hyperalgesia, inflammatory hypersensitivity condition, neuropathic pain, neuropathic cold allodynia, inflammatory somatic hyperalgesia, inflammatory visceral hyperalgesia, cardiovascular disease aggravated by cold and pulmonary disease aggravated by cold.
