AMARI, GABRIELE,RICCABONI, MAURO,CALIGIURI, ANTONIO
申请号：
ES11724157
公开号：
ES2545812T3
申请日:
2011.05.30
申请国别(地区):
ES
年份:
2015
代理人:
摘要：
A compound of the general Formula (I) ** Formula ** wherein: R1 is selected from the group consisting of aryl, heteroaryl, aryl (C1-C6) alkyl and heteroaryl (C1-C6) alkyl, optionally substituted by one or more substituents selected from the group consisting of halogen atoms, OH, oxo, SH, NH2, NO2, CN, CON (R5) 2, NHCOR5, COR5, CO2R5, (C1-C6) alkylsulfanyl, (C1-C6) alkylsulfinyl, (C1-C6) alkylsulfonyl, (C1-C6) alkyl, (C1-C6) haloalkyl, (C1-C6) alkoxy and (C1-C6) haloalkoxy； R2 is H or is selected from the group consisting of (C1-C6) alkyl, (C3-C8) cycloalkyl and aryl (C1-C6) alkyl, optionally substituted by one or more substituents selected from the group consisting of halogen atoms, OH, oxo, SH, NH2, NO2, CN, CON (R5) 2, NHCOR5, COR5, CO2R5, (C1-C6) alkylsulfanyl, (C1-C6) alkylsulfinyl, (C1-C6) alkylsulfonyl, (C1-C6) alkyl, (C1-C6) haloalkyl, (C1-C6) alkoxy and (C1-C6) haloalkoxy； R3 is selected from the group consisting of phenyl, pyridyl and benzothiophenyl, optionally substituted by one or more substituents selected from the group consisting of halogen atoms, OH, oxo, SH, NH2, NO2, CN, CON (R5) 2, COR5 , CO2R5, (C1-C6) alkylsulfanyl, (C1-C6) alkylsulfinyl, (C1-C6) alkylsulfonyl, (C1-C6) alkyl, (C1-C6) haloalkyl, (C1-C6) alkoxy and (C1-C6) haloalkoxy and aryl (C1-C6) alkoxy； R5 is selected, independently at each occurrence, from the group consisting of H, (C1-C6) alkyl, (C2-C6) alkenyl, (C3-C8) cycloalkyl, heteroaryl and aryl, optionally substituted by one or more substituents selected from the group consisting of halogen atoms, OH, oxo, SH, NH2, NO2, CN, CONH2, COOH, (C1-C6) alkoxycarbonyl, (C1-C6) alkylsulfanyl, (C1-C6) alkylsulfinyl, (C1-C6 ) alkylsulfonyl, (C1-C6) alkyl, (C1-C6) haloalkyl, (C1-C6) alkoxy and (C1-C6) haloalkoxy； Q represents a group of the formula (i) or (ii) ** Formula ** where R4 is a group of the formula (Y) --- (CH2) p --- P --- (CH2q --- W (Y) where p is 0 or an integer from 1 to 4； q is 0 or an integer from 1 to 4； P is absent or is selec
