BELL, ANDREW SIMON,BROWN, ALAN DANIEL,DE GROOT, MARCEL JOHN,LEWTHWAITE, RUSSELL ANDREW,MARSH, IAN ROGER,MILLAN, DAVID SIMON,PEREZ PACHECO, MANUEL,RAWSON, DAVID JAMES,SCIAMMETTA, NUNZIO,STORER, ROBERT
申请号:
CA2804877
公开号:
CA2804877A1
申请日:
2011.07.07
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The invention relates to sulfonamide derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to a new sulfonamide Nav1.7 inhibitors of formula (I):or a pharmaceutically acceptable salt thereof, wherein Ar1, X, R1, R2, R3, R4 and R5 are as defined in the description. Nav 1.7 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly pain.