GILBERT, IAN HUGH,NORCROSS, NEIL,BARAGANA RUIBAL, BEATRIZ,PORZELLE, ACHIM
申请号:
SG11201406548W
公开号:
SG11201406548WA
申请日:
2013.03.14
申请国别(地区):
SG
年份:
2015
代理人:
摘要:
The present invention relates to a novel class of quinolone-4-carboxamide Pf3D7 inhibitors of general formula (I) (Formula (I)) wherein R1, R2, R3, R4, R5, R6, R7, R8 and X are as defined herein, to their use in medicine, and in the treatment of malaria in particular, to compositions containing them, to processes for their preparation and to intermediates used in such processes.