Alan Daniel Brown,David James Rawson,Robert Ian Storer,Nigel Alan Swain
申请号：
US13808653
公开号：
US09102621B2
申请日:
2011.07.04
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The invention relates to sulfonamide derivatives, to their use in medicine, to 5 compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to a new sulfonamide Nav1.7 inhibitors of formula (I): 10 X NH O S O O R1 R2 R5 R4 R3 Het1 (I) or a pharmaceutically acceptable salt thereof, wherein X, Het1, R1, R2, R3, R4 and R5 are as defined in the description. 15 Nav 1.7 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly pain.
