RAWSON, DAVID JAMES,STORER, ROBERT IAN,SWAIN, NIGEL ALAN
申请号:
CA2857603
公开号:
CA2857603A1
申请日:
2012.12.06
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
The invention relates to sulfonamide derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to a new sulfonamide Nav 1.7 inhibitors of Formula (I): or a pharmaceutically acceptable salt thereof, wherein X, Z, R1a, R1b, R2, R3, R4 and R5 are as defined in the description. Nav 1.7 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly pain.