David James Rawson,Robert Ian Storer,Nigel Alan Swain
申请号：
US14358494
公开号：
US20140315879A1
申请日:
2012.12.06
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention relates to sulfonamide derivatives, of formula (I):or a pharmaceutically acceptable salts thereof, wherein X, Z, R1a, R1b, R2, R3, R4 and R5 are as defined in the description, and to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. The compounds of formula (I) are Nav1.7 inhibitors useful in the treatment of a wide range of disorders, particularly pain.
