Alan Daniel Brown;Robert Ian Storer;Thomas Ryckmans;David James Rawson;Brian Edward Marron;Christopher William West;Marcel John De Groot;Paul Anthony Stupple;Nigel Alan Swain
发明人:
Alan Daniel Brown,Marcel John De Groot,Brian Edward Marron,David James Rawson,Thomas Ryckmans,Robert Ian Storer,Paul Anthony Stupple,Nigel Alan Swain,Christopher William West
申请号：
US13178534
公开号：
US20120010182A1
申请日:
2011.07.08
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention relates to sulfonamide derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes.More particularly the invention relates to new sulfonamide Nav1.7 inhibitors of formula (I):or pharmaceutically acceptable salts thereof, wherein Z1, Ra, Rb, R1, R2, R3, R4 and R5 are as defined in the description.Nav 1.7 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly pain.
