Andrew Simon Bell,Alan Daniel Brown,Russell Andrew Lewthwaite,Manuel Perez-Pacheco,David James Rawson,Robert Ian Storer,Nigel Alan Swain
申请号：
US13808658
公开号：
US20130116285A1
申请日:
2011.07.06
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The invention relates to sulfonamide derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to a new sulfonamide Nav1.7 inhibitors of formula 10 (I):(I) or a pharmaceutically acceptable salt thereof, wherein Z, R1, R2, R3, R4 and R5 are as defined in the description. Nav 1.7 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly pain.
