VAITHIANATHAN PALANIAPPAN,WILLOW DILUZIO,JASON BROWN,IRVING H. FOX,CATHERINE SCHOLZ,PHUONG M. NGUYEN,CSANAD M. VARGA,ERICA HELEN JENKINS,MARIA ROSARIO
申请号:
PT12722973
公开号:
PT2704742T
申请日:
2012.05.02
申请国别(地区):
PT
年份:
2017
代理人:
摘要:
Antibody formulations are described comprising a mixture of an anti-±4²7 antibody, an antioxidant or chelator, and at least one free amino acid. The disclosed formulations may have improved stability, reduced aggregate formation, or both. The present invention further provides a safe dosing regimen of these antibody formulations that is easy to follow, and which results in a therapeutically effective amount of the anti-a4²7 antibody in vivo.