FORMULATION FOR ANTI- ALPHA4BETA7 ANTIBODY

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专利权人:

MILLENNIUM PHARMACEUTICALS; INC

发明人:

DILUZIO WILLOW,NGUYEN PHOUNG M,VARGA CSANAD M,PALANIAPPAN VAITHIANATHAN,BROWN JASON,FOX IRVING H.,SCHOLZ CATHERINE,JENKINS HELEN,ROSARIO MARIA

申请号：

CO13259852

公开号：

CO6801648A2

申请日:

2013.11.01

申请国别(地区):

CO

年份:

2013

代理人:

摘要：

Antibody formulations are described comprising a mixture of an anti-±4²7 antibody, an antioxidant or chelator, and at least one free amino acid. The disclosed formulations may have improved stability, reduced aggregate formation, or both. The present invention further provides a safe dosing regimen of these antibody formulations that is easy to follow, and which results in a therapeutically effective amount of the anti-a4²7 antibody in vivo.

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