CATHERINE SCHOLZ,CSANAD M. VARGA,HELEN JENKINS,IRVING H. FOX,JASON BROWN,MARIA ROSARIO,PHUONG M. NGUYEN,VAITHIANATHAN PALANIAPPAN,WILLOW DILUZIO
申请号：
BR112013028169
公开号：
BR112013028169A2
申请日:
2012.05.02
申请国别(地区):
BR
年份:
2017
代理人:
摘要：
Antibody formulations are described comprising a mixture of an anti-±4²7 antibody, an antioxidant or chelator, and at least one free amino acid. The disclosed formulations may have improved stability, reduced aggregate formation, or both. The present invention further provides a safe dosing regimen of these antibody formulations that is easy to follow, and which results in a therapeutically effective amount of the anti-a4²7 antibody in vivo.
