HITE, MICHAEL,FEDERICI, CATHY,BRUNELLE, ALAN,TURNER, STEPHEN
申请号：
HK07112497.6
公开号：
HK1107002B
申请日:
2007.11.15
申请国别(地区):
HK
年份:
2013
代理人:
摘要：
The present invention is a solid dosage form for oral administration of ibuprofen comprising a modified release formulation of ibuprofen which provides an immediate burst effect and thereafter a sustained release of sufficient ibuprofen to maintain blood levels at least 6.4 mug/ml over an extended period of at least 8 hours following administration of a single dose. The dosage form releases ibuprofen at a rate sufficient to initially deliver a effective amount of ibuprofen within about 2.0 hours following administration. The dosage form then subsequently delivers the remaining amount of ibuprofen at a relatively constant rate sufficient to maintain a level of ibuprofen over a predetermined delivery period of for at least 8 hours.
