HITE MICHAEL,FEDERICI CATHY,BRUNELLE ALAN,TURNER STEPHEN
申请号：
IN2407/DELNP/2007
公开号：
IN264128B
申请日:
2007.03.29
申请国别(地区):
IN
年份:
2014
代理人:
摘要：
The present invention is a solid dosage form for oral administration of ibuprofen comprising a modified release formulation of ibuprofen which provides an immediate burst effect and thereafter a sustained release of sufficient ibuprofen to maintain blood levels at least 6,4 µg/ml over an extended period of at least 8 hours following administration of a single dose. The dosage form releases ibuprofen at a rate sufficient to initially deliver a effective amount of ibuprofen within about 2.0 hours following administration. The dosage form then subsequently delivers the remaining amount of ibuprofen at a relatively constant rate sufficient to maintain a level of ibuprofen over a predetermined delivery period of for at least 8 hours.
