Combination comprising at least one spliceosome modulator and at least one inhibitor chosen from BCL2 inhibitors, BCL2/BCLxL inhibitors, and BCLxL inhibitors and methods of use
AIRD, Daniel,CORSON, Laura,ZHU, Ping,WARMUTH, Markus,BUONAMICI, Silvia,SMITH, Peter Gerard,FEKKES, Peter
申请号:
AU2018360559
公开号:
AU2018360559A1
申请日:
2018.10.30
申请国别(地区):
AU
年份:
2020
代理人:
摘要:
The present disclosure provides pharmaceutical combinations comprising at least one spliceosome modulator and at least one inhibitor chosen from BCL2, BCL2/BCLxL, and BCLxL inhibitors. Also provided are methods of treating cancer comprising administering a therapeutically effective amount of at least one spliceosome modulator and a therapeutically effective amount of at least one inhibitor chosen from BCL2, BCL2/BCLxL, and BCLxL inhibitors.