A protocol and hardware agnostic interface is provided for physical devices. A layer is determined to be available based on detecting a modem slot of the physical device being mated to a first modem cartridge. Responsive to the mating detection, a data channel is set up between the modem slot and the first modem cartridge. An application data transfer command is transmitted from the first modem cartridge over the wireless portion of the data communication network using the first wireless protocol to the first modem server. The first modem server reverts the data transfer command back to the original format and relays the reverted data transfer command to a command server over the wide area network portion of the data communication network for fulfillment of the physical device request.