A respiration system with a respirator (2) and with a breathing system (1), which is detachably coupled with the respirator. The coupling between the respirator and the breathing system takes place by at least two connector systems (3). The coupling between the respirator and the breathing system is designed such that the volume flow through the connector systems always takes place in only one direction. A pressure sensor (9 9′) is preferably combined with at least one of the connector systems (3) such that a unidirectional volume flow, by which the direction of migration of bacteria through the connector system is influenced in the desired manner, becomes established within this connector system (3), as a result of which the connector system and the coupled sensor are kept free from bacteria, viruses and other contaminants.