Konteatis, Zenon D.,Popovici-Muller, Janeta,Travins, Jeremy
申请号:
AU2014287121
公开号:
AU2014287121B2
申请日:
2014.07.10
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
Provided are compounds of formula (I), wherein: ring A and ring B are each independently an optionally substituted 5-6 membered monocyclic aryl or heteroaryl; one of X, Y and W is CH and the two others are N; and Z is H or -C(R1)(R2)(R3). The compounds are inhibitors of isocitrate dehydronenase 2 (IDH2) mutants useful for treating cancer.