Zenon D. Konteatis,Janeta Popovici-Muller,Jeremy M. Travins
申请号:
US14903947
公开号:
US10376510B2
申请日:
2014.07.10
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Provided are compounds of formula (I), wherein: ring A and ring B are each independently an optionally substituted 5-6 membered monocyclic aryl or heteroaryl; one of X, Y and W is CH and the two others are N; and Z is H or —;C(R1)(R2)(R3). The compounds are inhibitors of isocitrate dehydronenase 2 (IDH2) mutants useful for treating cancer.