NORTIC HOLDINGS INC.;KUMAR Amresh;KAVURU Vimal;SUNTHANKAR Prasanna;KOTTAYIL S. George
发明人:
KOTTAYIL S. George,KUMAR Amresh,SUNTHANKAR Prasanna,KAVURU Vimal
申请号：
IL26233518
公开号：
IL262335D0
申请日:
2018.10.14
申请国别(地区):
IL
年份:
2018
代理人:
摘要：
A nimodipine injection concentrate and diluted formulation comprises nimodipine (base or salt), an effective amount of a hydrophilic surfactant, and a pharmaceutically acceptable carrier for injection which is an aqueous solution, an organic solvent, an oil, or a cyclodextrin, such that the nimodipine is substantially contained in a concentrated injection solution, suspension, emulsion or complex as a micelle or a colloidal particle or an inclusion complex and the formulation is stable and clear. In certain embodiments, the hydrophilic surfactant is polysorbate 80.
