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Synthesis of chiral 2-(1H-indazol-6-yl)-spiro[cyclopropane-1,3′-indolin]-2′-ones
专利权人:
Bryan T. Forrest;Yong Liu;Narendra Kumar B. Patel;Peter Brent Sampson;Heinz W. Pauls;Graham Cumming;Louise G. Edwards;Sze-Wan Li
发明人:
Graham Cumming,Narendra Kumar B. Patel,Bryan T. Forrest,Yong Liu,Sze-Wan Li,Peter Brent Sampson,Louise G. Edwards,Heinz W. Pauls
申请号:
US13639648
公开号:
US08921545B2
申请日:
2011.04.06
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention is directed to novel synthetic methods for preparing a spiro cyclopropyl indolinone compound represented by Structural Formula (A): (A) or its pharmaceutically acceptable salt thereof. Also included are synthetic intermediates described herein.
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