Graham Cumming,Narendra Kumar B. Patel,Bryan T. Forrest,Yong Liu,Sze-Wan Li,Peter Brent Sampson,Louise G. Edwards,Heinz W. Pauls
申请号:
US14580658
公开号:
US09579327B2
申请日:
2014.12.23
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention is directed to novel synthetic methods for preparing a spiro cyclopropyl indolinone compound represented by Structural Formula (A):or its pharmaceutically acceptable salt thereof. Also included are synthetic intermediates described herein.