A laser nanometer-scale optical diagnostic device, characterized by comprising: a darkened treatment room (101) a carrying platform (102) a first laser (103) emitting a laser enabling a nanometer-scale photosensitive agent injected in the body of an object of treatment to emit light a charge coupling image sensing device (CCD) (104) disposed in the darkened treatment room (101) an optical filter (105) disposed between the object of treatment and the CCD (104) an image processor (106) for processing an image captured by the CCD (104), and locating a light concentration region in the body of the object of treatment a central controller (107) for locating the light concentration region in the body of the object of treatment as a tumor area, and controlling a rotating platform (108) to rotate, the rotating platform (108) being connected to a second laser (109), and adjusting an emitting direction of the second laser (109) via rotation the second laser (109) disposed on the rotating platform (108), and emitting a laser to enable the nanometer-scale photosensitive agent to exhibit the effects of photo-thermal therapy and/or photodynamic treatment. The device monitors in real time the metabolization, distribution and concentration of the nanometer-scale photosensitive agent, accurately locates a tumor and realizes a noninvasive tumor treatment for an object of treatment.Linvention concerne un dispositif de diagnostic optique à léchelle nanométrique à laser qui est caractérisé par le fait quil comprend : une salle de traitement assombrie (101) une plate-forme de transport (102) un premier laser (103) émettant un laser permettant à un agent photosensible à léchelle nanométrique, injecté dans le corps dun sujet de traitement, démettre de la lumière un dispositif de détection dimage à couplage de charge (CCD) (104) disposé dans la salle de traitement assombrie (101) un filtre optique (105) disposé entre le sujet de traitement et le CCD (104) un processeur dimage (106) pou