JONES, TODD K.,CISAR, JUSTIN S.,GRICE, CHERYL A.,WANG, DONG-HUI,WEBER, OLIVIA D.
申请号:
CA2917050
公开号:
CA2917050A1
申请日:
2014.07.01
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
The invention provides pyrrolo-pyrrole carbamate and related organic compounds, compositions containing such compounds, medical kits, and methods for using such compounds and compositions to treat medical disorders, e.g., solid tumor cancer, obesity, Down's syndrome, Alzheimer's disease, or pain, in a patient. The octahydropyrrolo pyrrole carbamates could be derived from hexafluoroisopropanol, ?,?-disuccinimide and such. The activity of carbamates in MAGL, FAAH, and ABHD6 assays are also described.