Todd K. Jones,Justin S. Cisar,Cheryl A. Grice,Dong-Hui Wang,Olivia D. Weber
申请号:
US14902324
公开号:
US09828379B2
申请日:
2014.07.01
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The invention provides pyrrolo-pyrrole carbamate and related organic compounds, compositions containing such compounds, medical kits, and methods for using such compounds and compositions to treat medical disorders, e.g., solid tumor cancer, obesity, Down's syndrome, Alzheimer's disease, or pain, in a patient. The octahydropyrrolo pyrrole carbamates could be derived from hexafluoroisopropanol, N,N-disuccinimide and such. The activity of carbamates in MAGL, FAAH, and ABHD6 assays are also described.