A method for treating acute ischemic stroke in a human comprises administering tenecteplase to the human in a total dose of about 0.05 to 0.5 mg/kg, given as (a) an initial bolus dose of about 0.015 to 0.15 mg/kg, followed by infusion of an amount equaling the total dose minus the initial dose over a period of about 50-90 minutes, or (b) a bolus. Also described are kits for carrying out this method.本發明係關於一種治療人類之急性缺血性中風的方法,其包含將替奈普酶(tenecteplase)以約0.05至0.5 mg/kg之總劑量以如下給藥方式投與人類:(a)初始約0.015至0.15 mg/kg之快速注射劑量,繼之在約50-90分鐘期間輸注等於總劑量減去初始劑量之量;或(b)快速注射。亦描述用於實施該方法之套組。(無元件符號說明)