CISZEWSKI, LECH,DE LA CRUZ, MARILYN,KARPINSKI, PIOTR H.,MUTZ, MICHAEL,RIEGERT, CHRISTIAN,VOGEL, CASPAR,SCHNEEBERGER, RICARDO
申请号:
CA2747437
公开号:
CA2747437C
申请日:
2009.12.16
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
This invention relates to a hemifumarate salt of 1-(4-{1-[(E)-4-cyclohexyl-3-trifluoromethyl-benzyloxyimino]-ethyl}-2-ethyl-benzyl)-azetidine-3-carboxylic acid (Compound I), topharmaceutical compositions comprising this salt, to processesfor forming this salt and to its use in medical treatment. In addition, thepresent invention also relates to new polymorphicforms of the hemifumarate salt form of Compound I, as well as topharmaceutical compositions comprising these polymorphicforms, to processes for obtaining them, and their use in medical treatment.