Marilyn De La Cruz;Lech Ciszewski;Ricardo Schneeberger;Christian Riegert;Michael Mutz;Caspar Vogel;Piotr H. Karpinski
发明人:
Lech Ciszewski,Marilyn De La Cruz,Piotr H. Karpinski,Michael Mutz,Christian Riegert,Caspar Vogel,Ricardo Schneeberger
申请号：
US13140478
公开号：
US20120115840A1
申请日:
2009.12.16
申请国别(地区):
US
年份:
2012
代理人:
摘要：
This invention relates to a hemifumarate salt of 1-(4-{1-[(E)-4-cyclohexyl-3-trifluoromethyl-benzyloxyimino]-ethyl}-2-ethyl-benzyl)-azetidine-3-carboxylic acid (Compound I), to pharmaceutical compositions comprising this salt, to processes for forming this salt and to its use in medical treatment. In addition, the present invention also relates to new polymorphic forms of the hemifumarate salt form of Compound I, as well as to pharmaceutical compositions comprising these polymorphic forms, to processes for obtaining them, and their use in medical treatment.
