CISZEWSKI, LECH,DE LA CRUZ, MARILYN,KARPINSKI, PIOTR H.,MUTZ, MICHAEL,RIEGERT, CHRISTIAN,VOGEL, CASPAR,SCHNEEBERGER, RICARDO
申请号:
MYPI 2011002413
公开号:
MY152669A
申请日:
2009.12.16
申请国别(地区):
MY
年份:
2014
代理人:
摘要:
THIS INVENTION RELATES TO A HEMIFUMARATE SALT OF 1-(4-{1-[(E)-4-CYCLOHEXYL-3-TRIFLUOROMETHYL-BENZYLOXYIMINO]-ETHYL}-2-ETHYL-BENZYL)-AZETIDINE-3-CARBOXYLIC ACID (COMPOUND I), TO PHARMACEUTICAL COMPOSITIONS COMPRISING THIS SALT, TO PROCESSES FOR FORMING THIS SALT AND TO ITS USE IN MEDICAL TREATMENT. IN ADDITION, THE PRESENT INVENTION ALSO RELATES TO NEW POLYMORPHIC FORMS OF THE HEMIFUMARATE SALT FORM OF COMPOUND I, AS WELL AS TO PHARMACEUTICAL COMPOSITIONS COMPRISING THESE POLYMORPHIC FORMS, TO PROCESSES FOR OBTAINING THEM, AND THEIR USE IN MEDICAL TREATMENT.