The present invention relates to a novel method for preparing 1 (4 (4 (3 4 dichloro 2 fluorophenylamino) 7 methoxyquinazolin 6 yloxy)piperidin 1 yl)prop 2 en 1 one in a simpler process as compared with conventional methods by allowing 4 (3 4 dichloro 2 fluorophenylamino) 7 methoxyquinazolin 6 ol to react with an N acyl piperidine derivative in an inert polar protic solvent in the presence of a base.