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Formulation of buprenorphine injection
专利权人:
CAMURUS AB
发明人:
TIBERG, Fredrik,JOHNSSON, Markus,HARWIGSSON, Ian
申请号:
CL2017001024
公开号:
CL2017001024A1
申请日:
2017.04.25
申请国别(地区):
CL
年份:
2017
代理人:
摘要:
<; p >; The present Invention provides a formulation N & amp; n & amp; Liquid injection comprising: a) a Matrix controlled release & amp; L & amp; Lipids comprising at least 50% of triacilo L & amp; Lipids; at least one Oxygen containing Solvent org & nbsp; nico; and at least 16% N Weight of at least one ACTIVE AGENT selected from buprenorphine and salts thereof,Calculated as the Free Base of buprenorphine. The Invention also provides & acute; S A & nbsp; composition & amp; n Release controlled Bertalanffy, formed by & nbsp; The Administration of the composition Bertalanffy Bertalanffy Liquid Injection to a subject, preferably a Human.The Invention also provides N & amp; n a M & eacute; & eacute; administration of buprenorphine Bertalanffy to a subject comprising injecting the liquid composition & acute; S N and all M & eacute; for the treatment of PainFor maintenance therapy of opioids for the treatment of Opioid Dependence through desintoxicaci Bertalanffy and / or maintenance or for the Treatment or prophylaxis of S & amp; symptoms of Opioid withdrawal and / or withdrawal of Coke & amp; injecting the composition & oa na Cute N; L & amp; quida. <; / p >;<;p>;LA PRESENTE INVENCIÓ;N PROPORCIONA UNA FORMULACIÓ;N LIQUIDA INYECTABLE QUE COMPRENDE: A) UNA MATRIZ DE LIBERACIÓ;N CONTROLADA DE LÍ;PIDOS QUE COMPRENDE AL MENOS 50% DE LÍ;PIDOS TRIACILO; AL MENOS UN OXIGENO QUE CONTIENE DISOLVENTE ORGÁ;NICO; POR LO MENOS 16% EN PESO DE AL MENOS UN AGENTE ACTIVO SELECCIONADO DE BUPRENORFINA Y SALES DE LA MISMA, CALCULADO COMO BASE LIBRE DE BUPRENORFINA. LA INVENCIÓ;N PROPORCIONA ADEMÁ;S UNA COMPOSICIÓ;N DE LIBERACIÓ;N CONTROLADA, FORMADA POR ; LA ADMINISTRACIÓ;N DE DICHA COMPOSICIÓ;N LIQUIDA INYECTABLE A UN SUJETO PREFERIBLEMENTE HUMANO. LA INVENCIÓ;N PROPORCIONA TAMBIÉ;N UN MÉ;TODO DE ADMINISTRACIÓ;N DE BUPRENORFINA A UN SUJETO QUE COMPRENDE INYECTAR DICHA COMPOSI
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