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METHOD FOR MANUFACTURING PYRAZOLE DERIVATIVE
专利权人:
发明人:
AKAHOSHI FUMIHIKO,KIRIHARA SHINJI
申请号:
IN10292/CHENP/2013
公开号:
IN300270B
申请日:
2012.05.31
申请国别(地区):
IN
年份:
2018
代理人:
摘要:
The present invention provides a prolinamide compound useful as a drug or the like and an industrially advantageous method for producing a piperazinyl pyrazole compound that is a production intermediate of the prolinamide compound. Specifically, the invention is a method for producing a compound represented by general formula (1) as represented by the following formula (where the symbols in the formula are the same as defined in the specification) or a salt thereof, wherein a compound represented by general formula (2) is produced, a pyrazole ring being formed via a reaction between a compound represented by general formula (3) and phosphorus pentasulfide and, once the compound represented by general formula (2) is deprotected, a carboxylate of a compound represented by general formula (6) is produced, the compound obtained by forming a carboxylic acid and a salt. WO2012165547A1
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