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Monosebacate of pyrazole derivative
专利权人:
Eiji Tsuru;Hideki Takeuchi
发明人:
Hideki Takeuchi,Eiji Tsuru
申请号:
US12810476
公开号:
US08399418B2
申请日:
2008.12.24
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention provides a novel form of 3-(3-{4-[3-(β-D-glucopyranosyloxy)-5-isopropyl-1H-pyrazol-4-ylmethyl]-3-methylphenoxy}propylamino)-2,2-dimethylpropionamide with improved storage stability. Since bis[3-(3-{4-[3-(β-D-glucopyranosyloxy)-5-isopropyl-1H-pyrazol-4-ylmethyl]-3-methylphenoxy}propylamino)-2,2-dimethylpropionamide]monosebacate has extremely excellent storage stability, it is useful as a drug substance. Furthermore, it shows an extremely good crystalline property and can be purified by a convenient method, and therefore is suitable for the industrial preparation.
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