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NUCLEIC ACID DELIVERY COMPOSITION AND CARRIER COMPOSITION, PHARMACEUTICAL COMPOSITION USING THE SAME, AND METHOD FOR NUCLEIC ACID DELIVERY
专利权人:
THE UNIVERSITY OF TOKYO
发明人:
KATAOKA, KAZUNORI,ISHII, TAKEHIKO,OSADA, KENSUKE,CHEN, QIXIAN,ITAKA, KEIJI,UCHIDA, SATOSHI
申请号:
CA2804815
公开号:
CA2804815A1
申请日:
2011.07.11
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
Disclosed is an excellent composition for nucleic acid delivery, which is reduced in cytotoxicity and has high nucleic acid introduction efficiency and high gene expression efficiency. Specifically disclosed is a composition for nucleic acid delivery, which contains: a block copolymer that has a non-charged hydrophilic polymer segment and a cationic polymer segment a cationic polymer and a nucleic acid. The mole percentage (B/H ratio) of the cationic groups contained in the block copolymer relative to the total cationic groups contained in the block copolymer and the cationic polymer is 25-90%.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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