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COMPOSITION FOR NUCLEIC ACID DELIVERY, CARRIER COMPOSITION, PHARMACEUTICAL COMPOSITION USING THE COMPOSITION FOR NUCLEIC ACID DELIVERY OR THE CARRIER COMPOSITION, AND METHOD FOR DELIVERING NUCLEIC ACID
专利权人:
THE UNIVERSITY OF TOKYO
发明人:
KATAOKA, KAZUNORI,ISHII, TAKEHIKO,OSADA, KENSUKE,CHEN, QIXIAN,ITAKA, KEIJI,UCHIDA, SATOSHI
申请号:
EP11803707
公开号:
EP2591792A4
申请日:
2011.07.11
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
An excellent nucleic acid delivery composition is provided which has reduced cytotoxicity and improved nucleic acid introduction efficiency and gene expression efficiency. The composition comprises: a block copolymer having an uncharged hydrophilic polymer segment and a cationic polymer segment a cationic polymer and a nucleic acid, wherein the mol percentage (B/H ratio) of the cationic groups of the block copolymer to the total cationic groups of the block copolymer and the cationic polymer is between 25% and 90%.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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