COMPOSITIONS AND METHODS FOR IMMUNOSTIMULATORY RNA OLIGONUCLEOTIDES

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专利权人:

Gunther Hartmann

发明人:

Gunther Hartmann,Veit Hornung

申请号：

US13293547

公开号：

US20120121551A1

申请日:

2011.11.10

申请国别(地区):

US

年份:

2012

代理人:

摘要：

The present invention provides 4-nucleotide (4mer) RNA motifs that confer immunostimulatory activity, in particular, IFN-α-inducing activity to a RNA oligonucleotide. The present invention also provides RNA oligonucleotides, including siRNA, with high or low immunostimulatory activity. The present invention further provides the use of the RNA oligonucleotides of the invention for therapeutic purposes.

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中国工程科技知识中心

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