MCEACHERN, ERNEST J.,MU, CHANGWEI,SELNICK, HAROLD G.,VOCADLO, DAVID J.,WANG, YAODE,WEI, ZHONGYONG,ZHOU, YUANXI,ZHU, YONGBAO,KAUL, RAMESH
申请号：
CA2822493
公开号：
CA2822493C
申请日:
2011.12.21
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The invention provides compounds with enhanced permeability for selectivelyinhibiting glycosidases, prodrugs ofthe compounds, and pharmaceutical compositions including the compounds orprodrugs of the compounds. The invention alsoprovides methods of treating diseases and disorders related to deficiency oroverexpression of 0-GlcNAcase, accumulation ordeficiency of O-GlcNAc.
