ANTICORPS SELECTIONNES SE LIANT A DES PHOSPHOLIPIDES ANIONIQUES ET DES AMINOPHOSPHOLIPIDES ET LEUR UTILISATION POUR UN TRAITEMENT

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专利权人:

BOARD OF REGENTS; THE UNIVERSITY OF TEXAS SYSTEM

发明人:

THORPE, PHILIP E.,HUANG, XIANMING,RAN, SOPHIA

申请号：

CA2894009

公开号：

CA2894009C

申请日:

2003.07.15

申请国别(地区):

CA

年份:

2016

代理人:

摘要：

Antibodies, compositions comprising such antibodies, and uses thereof in thetreatment of diseases such ascancer are described, in which the antibodies are observed to bind to aphosphatidylserine (PS)-coated ELISAplate in an ELISA conducted in the presence of 10% serum. Hybridomas and hostcells producing suchantibodies, as well as nucleic acids and expression vectors encoding suchantibodies are also provided.Antibodies described herein include antibody 3G4, deposited as ATCC AccessionNumber PTA 4545, andchimeric 3G4 antibodies comprising human antibody constant regions.

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