Construction of oncolytic herpes simplex viruses (oHSV) obligate vector and constructs for cancer therapy

• 收藏
• 分享

专利权人:

Limited;Immvira Co.

发明人:

Zhou, Grace Guoying,Chen, Xiaoqing,Liu, Xianjie

申请号：

AU2020204209

公开号：

AU2020204209A1

申请日:

2020.06.24

申请国别(地区):

AU

年份:

2020

代理人:

摘要：

#$%^&*AU2020204209A120200716.pdf#####CONSTRUCTION OF ONCOLYTIC HERPES SIMPLEX VIRUSES (oHSV) OBLIGATE VECTOR AND CONSTRUCTS FOR CANCER THERAPY Abstract An obligate oHSV vector comprising modified viral DNA genome is provided. A recombinant oHSV-1 construct comprising the obligate oHSV vector and a heterologous nucleic acid sequence encoding an immunostimulatory and/or immunotherapeutic agent is also provided. Compositions comprising the recombinant oHSV-1 construct can be used for treating cancers.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/