ALFARO-LOPEZ, JOSUE,SHARMA, ABHINANDINI,SOARES, CHRISTOPHER J.,COATS, EUGENE,GHOSH, SOUMITRA S.
申请号:
CA2806749
公开号:
CA2806749A1
申请日:
2011.07.27
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The disclosure provides GLP-1 receptor agonist compounds having stabilized regions corresponding to alpha-helical regions of the natural peptide compounds. The disclosure also provides benzamide-containing exendin-4 analogs and alkene-constrained exendin-4 analogs, both of which have stabilized regions corresponding to alpha-helical regions of exendin-4.