ASTRAZENECA PHARMACEUTICALS LP;AMYLIN PHARMACEUTICALS, INC.
发明人:
ABHINANDINI SHARMA,CHRISTOPHER J. SOARES,EUGENE COATS,JOSUE ALFARO-LOPEZ,SOUMITRA S. GHOSH
申请号：
BR112013002096
公开号：
BR112013002096A2
申请日:
2011.07.27
申请国别(地区):
BR
年份:
2019
代理人:
摘要：
The disclosure provides GLP-1 receptor agonist compounds having stabilized regions corresponding to alpha-helical regions of the natural peptide compounds. The disclosure also provides benzamide-containing exendin-4 analogs and alkene-constrained exendin-4 analogs, both of which have stabilized regions corresponding to alpha-helical regions of exendin-4.
