Soumitra S. Ghosh;Eugene Coats;Abhinandini Sharma;Josue Alfaro-Lopez;Christopher J. Soares
发明人:
Josue Alfaro-Lopez,Abhinandini Sharma,Christopher J. Soares,Eugene Coats,Soumitra S. Ghosh
申请号：
US13812445
公开号：
US09217022B2
申请日:
2011.07.27
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The disclosure provides GLP-1 receptor agonist compounds having stabilized regions corresponding to alpha-helical regions of the natural peptide compounds. The disclosure also provides benzamide-containing exendin-4 analogs and alkene-constrained exendin-4 analogs, both of which have stabilized regions corresponding to alpha-helical regions of exendin-4.
