SMITH ROGER A,DAMLE NITIN K,YURKOVETSKIY ALEKSANDR V,YIN MAO,LOWINGER TIMOTHY B,THOMAS JOSHUA D,STEVENSON CHERI A,GURIJALA VENU R
申请号：
IN201617015385
公开号：
IN201617015385A
申请日:
2016.05.03
申请国别(地区):
IN
年份:
2016
代理人:
摘要：
A polymeric scaffold useful for conjugating with a protein based recognition molecule (PBRM) to form a PBRM polymer drug conjugate is described herein. The scaffold includes one or more terminal maleimido groups. Also disclosed is a PBRM polymer drug conjugate prepared from the scaffold. Compositions comprising the conjugates methods of their preparation and methods of treating various disorders with the conjugates or their compositions are also described.
