A vascular optical fiber guidewire includes an optical fiber guidewire and a plug connected to the optical fiber guidewire. The plug may be a memory alloy plug including a handle, a fixing groove and a sleeve which are sequentially connected. A radius of a segment of the fixing groove is larger than a radius of a segment of the fixing groove. The fixing groove cooperates with an external connector to provide a locking effect. The sleeve is provided with an elastically deformable spiral structure. The memory alloy plug is sleeved on a metal tube sleeved outside the optical fiber guidewire and connected with the optical fiber guidewire. A part of the metal tube extending from the memory alloy plug forms a spiral shape by spirally cutting to protect and support the optical fiber guidewire. The insertion and extraction operations and rotating operations can be facilitated.
