Compounds derived from oxazolidin - 1.3 - 2 - one and 2 - oxo - 1.3 - imidazoline, inhibitor of Calcium activated Potassium Channel (kca3.1); Pharmaceutical composition; Treatment method; and use for the Treatment or prophylaxis of polycystic kidney disease, Asthma, Brain Edema and INTEST disease No inflammatory, among others.
The invention provides compounds having the general formula I wherein n, R1, R2a, R2b, R3a and R3b are as herein defined, composition comprising the compounds and methods of using the compounds.<;p>;COMPUESTOS DERIVADOS DE 2-OXO- OXAZOLIDIN CON ACTIVIDAD BLOQUEADORA DEL KCA3.1 Ú;TILES EN EL TRATAMIENTO DE LA ENFERMEDAD RENAL POLIQUISTICA, ASMA, EDEMA CEREBRAL, RECHAZO A TRASPLANTE, ATEROSCLEROSIS, FIBROSIS RENAL, CÁ;NCER, ENTRE OTRAS.<;/p>;